Warren Johnson's Home Page

Associate Professor of Biochemistry
University of Wisconsin-Green Bay

Office hours: MWF, 12:35-1:30 p.m. (fall 2011)
Phone: (920) 465-2275
Office Location: LS 451
e-mail: johnsonw@uwgb.edu

I am a member of three departments

  • Human Biology Interdisciplinatry Unit
  • Chemistry Discipline
  • Biology Discipline

If you have an interest in a major in any of these programs, I would be honored to serve as your advisor. Please contact me for an appointment to discuss your professional growth.

Helpful links

Jmol workshop for beginners: Learn how to make molecular models on the computer for any structure in the protein data base.

UW-Green Bay home page
Human Biology home page
Natural and Applied Sciences home page

 

Research Interest

Currently my main research interest is in isolating catabolite modulator factor (CMF), a global gene regulatory small molecule (molecular mass < 1000g) that is heat stable from the E. coli. When CMF is added to cultures of E. coli, it antagonizes the effect of cAMP on gene expression. Early work on CMF was done by Ullmann, Tiller and Monod, (1976) and Dessein, Tillier, and Ullmann (1978) and nothing has since been reported.

Currently, work is being done to optimizing the growth conditions of E. coli to produce the maximum amount of CMF. Additional improvements need to be developed for the assay for CMF. It is difficult and cumbersome to use our current assay.

References:
Dessein, A., Tillier, F., and Ullmann, A., 1978, Catabolite Modulation Factor: Physiological Properties and in vivo Effects. Molec. gen. Genet. 162:89-94.
Ullmann, A., Tiller, F., and Monod, J., 1976, Catabolite modulator factor: A possible mediator of catabolite repression in bacteria. Proc. Natl. Acad. Sci. USA 73:3476-3479.

 

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